Comparative effectiveness of interventions to facilitate deprescription of benzodiazepines and other sedative hypnotics: systematic review and meta-analysis
Our latest systematic review and meta-analysis on Benzodiazepine and Sedative Hypnotic deprescribing has just been published in the BMJ!
After extensive work together with the MAGIC Evidence Ecosystem Foundation team, we're thrilled to share that our systematic review and meta-analysis on interventions to facilitate deprescribing Benzodiazepines and other Sedative Hypnotics (BSH) is now live!
In this paper, we reviewed the latest evidence from randomized trials, assessing the effectiveness of strategies to deprescribe BSH. This comprehensive review identified 58 publications reporting on 49 unique trials with more than 39,000 patients.
Key Findings:
• Patient education, medication review, and pharmacist-led educational interventions may increase the proportion of patients who discontinue BSH compared to usual care.
• Multicomponent interventions show promise, potentially being more effective than single approaches.
• However, evidence on the effectiveness of these interventions remains low certainty, highlighting a critical need for more robust research.
This work underscores the importance of tailored support for deprescribing BSH, especially given patient concerns about hazards and withdrawal.
Huge thanks to the entire team for their dedication to this vital research!
📖 Read more in:
➡️ Our publications page
➡️ The BMJ
BE-SAFE in a nutshell
The BE-SAFE project is targeting patient safety by addressing knowledge and practice gaps related to the reduction of medications used for sleep problems in Europe. Experts and patients are involved to promote an interdisciplinary and inter-sectorial approach. BE-SAFE is a European research project funded by the European Commission Horizon programme under the work programme HORIZON-HLTH-2021-CARE-05-01: Enhancing quality of care and patient safety) and by the Swiss State Secretariat for Education, Research and Innovation (SERI) (contract No 22.00116). The project duration will be from 2022 to 2027.
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Press contact |
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Prof. Anne Spinewine |
Laura Fernández Maldonado |
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Project coordinator |
Communication Coordinator |
